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Can an NVIDIA GeForce RTX 4090 run Qwen2.5-3B-Instruct?

Yes. Qwen2.5-3B-Instruct needs 4.01GB at Q8_0 with llama.cpp and 8K context; the NVIDIA GeForce RTX 4090 has 24GB of VRAM (23.5GB usable) — grade A+, with decode speed in the interactive tier.

NVIDIA GeForce RTX 4090 · Qwen2.5-3B-Instruct · Q8_0

Fits — grade A+

Interactive
weights 3.29 GBKV cache 0.30 GBoverhead 0.42 GBpool 23.5 GBneeds 4.01 GB

assumes llama.cpp · batch 1 · 8K context · fp16 KV cache

$1,599 MSRP · as of 2026-07-08

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Every quant, graded

NVIDIA GeForce RTX 4090 × Qwen2.5-3B-Instruct, llama.cpp, 8K context.

QuantFile sizeFitSpeed tier
Q8_03.3 GBFits · A+interactive
Q6_K2.5 GBFits · A+interactive
Q5_K_M2.2 GBFits · A+interactive
Q4_K_M1.9 GBFits · A+interactive

Qwen2.5-3B-Instruct on similar hardware

More models on the NVIDIA GeForce RTX 4090

Verdict computed from published specs and measured GGUF file sizes — see how the math works.